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Single-molecule techniques in biophysics: a review of the progress in methods and applications

Abstract:

Single-molecule biophysics has transformed our understanding of biology, but also of the physics of life. More exotic than simple soft matter, biomatter lives far from thermal equilibrium, covering multiple lengths from the nanoscale of single molecules to up to several orders of magnitude higher in cells, tissues and organisms. Biomolecules are often characterized by underlying instability: multiple metastable free energy states exist, separated by levels of just a few multiples of the therm...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1088/1361-6633/aa8a02

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Physics
Sub department:
Condensed Matter Physics
Role:
Author
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Role:
Author
ORCID:
0000-0002-5501-8131
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Role:
Author
ORCID:
0000-0002-1715-1249
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Name:
Engineering and Physical Sciences Research Council
Grant:
DTA PhD studentship
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Name:
Biotechnology and Biological Sciences Research Council
Grant:
BB/N006453/1
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Name:
Medical Research Council
Grant:
MR/K01580X/1
Publisher:
Institute of Physics
Journal:
Reports on Progress in Physics More from this journal
Volume:
81
Issue:
2
Pages:
024601
Publication date:
2017-12-19
Acceptance date:
2017-08-31
DOI:
EISSN:
1361-6633
ISSN:
0034-4885
Pmid:
28869217
Language:
English
Keywords:
Pubs id:
pubs:813684
UUID:
uuid:1b3fe28d-7ddd-4d1d-902e-0f9341e2cfc5
Local pid:
pubs:813684
Source identifiers:
813684
Deposit date:
2018-04-11

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