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Whole-genome comparative analysis of two carbapenem-resistant ST-258 klebsiella pneumoniae strains isolated during a North-Eastern Ohio outbreak: differences within the high heterogeneity zones

Abstract:

Klebsiella pneumoniae has become one of the most dangerous causative agents of hospital infections due to the acquisition of resistance to carbapenems, one of the last resort families of antibiotics. Resistance is usually mediated by carbapenemases coded for by different classes of genes. A prolonged outbreak of carbapenem-resistant K. pneumoniae infections has been recently described in northeastern Ohio. Most strains isolated from patients during this outbre...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/gbe/evw135

Authors


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Role:
Author
ORCID:
0000-0002-9176-924X
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Role:
Author
ORCID:
0000-0002-3972-9208
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Name:
NIAID NIH HHS
Grant:
R21 AI114508
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Name:
NIMHD NIH HHS
Grant:
T37 MD001368
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Name:
NIMH NIH HHS
Grant:
F32 MH083469
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Name:
Wellcome Trust
Grant:
WT083469
200782/Z/16/Z
More from this funder
Name:
NCATS NIH HHS
Grant:
KL2 TR001862
UL1 TR001863
Publisher:
Oxford University Press
Journal:
Genome Biology and Evolution More from this journal
Volume:
8
Issue:
6
Pages:
2036–2043
Publication date:
2016-06-11
Acceptance date:
2016-05-31
DOI:
EISSN:
1759-6653
ISSN:
1759-6653
Pmid:
27289094
Language:
English
Keywords:
Pubs id:
pubs:627639
UUID:
uuid:1b3f69d6-7233-4bda-9162-eb43f62af5bf
Local pid:
pubs:627639
Source identifiers:
627639
Deposit date:
2019-07-03

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