Journal article
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis.
- Abstract:
-
Dissecting the molecular mechanisms used by developmental regulators is essential to understand tissue specification/differentiation. SCL/TAL-1 is a basic helix-loop-helix transcription factor absolutely critical for hematopoietic stem/progenitor cell specification and lineage maturation. Using in vitro and forced expression experimental systems, we previously suggested that SCL might have DNA-binding-independent functions. Here, to assess the requirements for SCL DNA-binding activity in vivo...
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- Publication status:
- Published
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- Publisher copy:
- 10.1182/blood-2007-12-128900
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Authors
Bibliographic Details
- Journal:
- Blood
- Volume:
- 112
- Issue:
- 4
- Pages:
- 1056-1067
- Publication date:
- 2008-08-01
- DOI:
- EISSN:
-
1528-0020
- ISSN:
-
0006-4971
- Source identifiers:
-
34273
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:34273
- UUID:
-
uuid:1b3e5652-1418-4435-971e-14c3723d183d
- Local pid:
- pubs:34273
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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