Connected speech as a marker of disease progression in autopsy-proven Alzheimer's disease.

Journal article

Although an insidious history of episodic memory difficulty is a typical presenting symptom of Alzheimer's disease, detailed neuropsychological profiling frequently demonstrates deficits in other cognitive domains, including language. Previous studies from our group have shown that language changes may be reflected in connected speech production in the earliest stages of typical Alzheimer's disease. The aim of the present study was to identify features of connected speech that could be used t...

Expand abstract

Authors: Ahmed, S; Haigh, A; de Jager, C; Garrard, P

• Publication status: Published
• Journal: Brain : a journal of neurology
• Volume: 136
• Issue: Pt 12
• Pages: 3727-3737
• Publication date: 2013-12-01
• DOI: 10.1093/brain/awt269
• EISSN: 1460-2156
• ISSN: 0006-8950
• Language: English
• Keywords: Female; Humans; Longitudinal Studies; Speech; Disease Progression; Cognition Disorders; Neuropsychological Tests; Middle Aged; Aged, 80 and over; Male; Aged; Autopsy; Language Disorders; Linear Models; Language Tests; Alzheimer Disease