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Journal article

Molecular detection and speciation of pathogenic Leptospira spp. in blood from patients with culture-negative leptospirosis.

Abstract:

BACKGROUND: Pathogenic Leptospira spp. present in the blood of patients with leptospirosis during the first week of symptoms can be detected using culture or PCR. A proportion of patients who are positive by PCR are negative by culture. Leptospira spp. are fastidious bacteria, and we hypothesized that a false-negative culture result may represent infection with a distinct bacterial subset that fail to grow in standard culture medium. METHODS: We evaluated our hypothesis during a prospective ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2334-11-338

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Publisher:
BioMed Central Publisher's website
Journal:
BMC infectious diseases Journal website
Volume:
11
Issue:
1
Pages:
338
Publication date:
2011-01-01
DOI:
EISSN:
1471-2334
ISSN:
1471-2334
Source identifiers:
221392
Language:
English
Keywords:
UUID:
uuid:1b33a9b1-a75e-40ac-b338-4d1b45d1257b
Local pid:
pubs:221392
Deposit date:
2012-12-19

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