- Abstract:
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BACKGROUND: Pathogenic Leptospira spp. present in the blood of patients with leptospirosis during the first week of symptoms can be detected using culture or PCR. A proportion of patients who are positive by PCR are negative by culture. Leptospira spp. are fastidious bacteria, and we hypothesized that a false-negative culture result may represent infection with a distinct bacterial subset that fail to grow in standard culture medium. METHODS: We evaluated our hypothesis during a prospective ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(doc, 46.0kb)
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(pdf, 1.3mb)
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- Publisher copy:
- 10.1186/1471-2334-11-338
-
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- Publisher:
- BioMed Central Ltd. Publisher's website
- Journal:
- BMC infectious diseases Journal website
- Volume:
- 11
- Issue:
- 1
- Pages:
- 338
- Publication date:
- 2011
- DOI:
- EISSN:
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1471-2334
- ISSN:
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1471-2334
- URN:
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uuid:1b33a9b1-a75e-40ac-b338-4d1b45d1257b
- Source identifiers:
-
221392
- Local pid:
- pubs:221392
- Copyright holder:
- Boonsilp et al.
- Copyright date:
- 2011
- Notes:
- © 2011 Boonsilp et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Molecular detection and speciation of pathogenic Leptospira spp. in blood from patients with culture-negative leptospirosis.
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