Journal article
Molecular detection and speciation of pathogenic Leptospira spp. in blood from patients with culture-negative leptospirosis.
- Abstract:
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BACKGROUND: Pathogenic Leptospira spp. present in the blood of patients with leptospirosis during the first week of symptoms can be detected using culture or PCR. A proportion of patients who are positive by PCR are negative by culture. Leptospira spp. are fastidious bacteria, and we hypothesized that a false-negative culture result may represent infection with a distinct bacterial subset that fail to grow in standard culture medium. METHODS: We evaluated our hypothesis during a prospective ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, doc, 46.0KB)
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(Version of record, pdf, 1.3MB)
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- Publisher copy:
- 10.1186/1471-2334-11-338
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Authors
Funding
Wellcome Trust
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Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC infectious diseases Journal website
- Volume:
- 11
- Issue:
- 1
- Pages:
- 338
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
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1471-2334
- ISSN:
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1471-2334
- Source identifiers:
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221392
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:1b33a9b1-a75e-40ac-b338-4d1b45d1257b
- Local pid:
- pubs:221392
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Boonsilp et al
- Copyright date:
- 2011
- Notes:
- © 2011 Boonsilp et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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