Journal article
Next-generation sequencing identifies germline MRE11A variants as markers of radiotherapy outcomes in muscle-invasive bladder cancer
- Abstract:
-
Background Muscle-invasive bladder cancer (MIBC) can be cured by radical radiotherapy (RT). We previously found tumour MRE11 expression to be predictive of survival following RT in MIBC, and this was independently validated in a separate institute. Here, we investigated germline MRE11A variants as possible predictors of RT outcomes in MIBC, using next-generation sequencing (NGS). Patients and methods The MRE11A gene was amplified in germline DNA from 186 prospectively recruited MIBC patients ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Annals of Oncology Journal website
- Volume:
- 25
- Issue:
- 4
- Pages:
- 877-883
- Publication date:
- 2014-03-12
- Acceptance date:
- 2013-12-31
- DOI:
- EISSN:
-
1569-8041
- ISSN:
-
0923-7534
- Pmid:
-
24623370
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:457659
- UUID:
-
uuid:1b22cd1a-419d-4e77-a5cd-99113f73a8f9
- Local pid:
- pubs:457659
- Source identifiers:
-
457659
- Deposit date:
- 2018-09-24
Terms of use
- Copyright holder:
- Teo et al
- Copyright date:
- 2014
- Notes:
- © The Author 2014. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
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