Journal article icon

Journal article

Analysis of Rab GTPases

Abstract:

This unit describes methods to identify proteins interacting with, and regulating, Rab GTPases. Rabs form the largest subgroup of Ras superfamily GTPases, and act as molecular switches controlling the specificity of membrane trafficking. The regulation and the signal readout of Rabs are mediated by four groups of proteins, the GDP-GTP exchange factors (GEFs), GTPase activating proteins (GAPs), Rab chaperones, and effector proteins. Rabs are activated at the membrane surface by specific GEFs t...

Expand abstract

Actions


Access Document


Authors


Langemeyer, L More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Journal:
Current Protocols in Cell Biology
Issue:
SUPPL.57
Publication date:
2012
DOI:
EISSN:
1934-2616
ISSN:
1934-2500
URN:
uuid:1b20897a-d53a-46a5-9f78-98ccfbc12400
Source identifiers:
417139
Local pid:
pubs:417139
Language:
English
Keywords:

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP