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Journal article

The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data platform

Abstract:

Background: Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses to address the many outstanding research questions. This systematic review aims to describe the characteristics and treatment practices of clinical studies in CD and assess the breadth and availability of research data for t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-6333-0109
More by this author
Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-2158-846X
More by this author
Institution:
University of Oxford
Role:
Author
ORCID:
0000-0001-8657-9639
More by this author
Institution:
University of Oxford
Role:
Author
ORCID:
0000-0003-4417-0653
More by this author
Institution:
University of Oxford
Role:
Author


Publisher:
Public Library of Science
Journal:
PLoS Neglected Tropical Diseases More from this journal
Volume:
15
Issue:
8
Pages:
e0009697-e0009697
Publication date:
2021-08-16
DOI:
EISSN:
1935-2735
ISSN:
1935-2727


Language:
English
Keywords:
Pubs id:
1192153
Local pid:
pubs:1192153
Source identifiers:
W3196073145
Deposit date:
2026-03-25
ARK identifier:
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