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Comparison of performance of exponential, Cox proportional hazards, weibull and frailty survival models for analysis of small sample size data

Abstract:

Background: The Cox Proportional Hazards(PH) model is commonest survival data model used in clinical trials. However, little is known as to whether or not this approach is robust to the size of the study. We compared performance of Cox, Weibull, Exponential and Frailty models in a randomized study that had a small sample size in general. Methods: Models were fitted to data from a three-arm randomized efficacy trial of Kaposi’s sarcoma at Queen Elizabeth Central Hospital (QECH) of children age...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.7243/2053-7662-4-2

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Publisher:
Herbert Open Access Journals
Journal:
Journal of Medical Statistics and Informatics More from this journal
Volume:
4
Issue:
1
Pages:
2-2
Publication date:
2016-02-05
Acceptance date:
2016-01-25
DOI:
EISSN:
2053-7662
Pubs id:
pubs:619241
UUID:
uuid:1b06b659-6534-4641-9900-24efc939c1ab
Local pid:
pubs:619241
Source identifiers:
619241
Deposit date:
2016-05-04

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