Journal article icon

Journal article

Adjunctive dexamethasone in HIV-associated cryptococcal meningitis

Abstract:

Cryptococcal meningitis associated with human immunodeficiency virus (HIV) infection causes more than 600,000 deaths each year worldwide. Treatment has changed little in 20 years, and there are no imminent new anticryptococcal agents. The use of adjuvant glucocorticoids reduces mortality among patients with other forms of meningitis in some populations, but their use is untested in patients with cryptococcal meningitis.In this double-blind, randomized, placebo-controlled trial, we recruited a...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1056/nejmoa1509024

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More from this funder
Name:
Wellcome Trust
Funding agency for:
Day, J
Grant:
WT097147MA
WT097147MA
More from this funder
Name:
Medical Research Council
Grant:
G1100684/1
More from this funder
Name:
Department for International Development
Grant:
G1100684/1
Publisher:
Massachusetts Medical Society
Journal:
New England Journal of Medicine More from this journal
Volume:
374
Issue:
6
Pages:
542-554
Publication date:
2016-02-01
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Language:
English
Keywords:
Pubs id:
pubs:605931
UUID:
uuid:1af68ef6-a567-4c49-a7b9-f550c4901a6e
Local pid:
pubs:605931
Source identifiers:
605931
Deposit date:
2016-02-27

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP