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Impact of both donor and recipient strains on cardiac allograft survival after blockade of the CD40-CD154 costimulatory pathway.

Abstract:

BACKGROUND: The effectiveness of anti-CD154 monoclonal antibodies in prolonging the survival of mouse allografts is dependent on the strain combination. In this report, we examined the impact of the donor and the recipient strains on the success of CD40-CD154 blockade. MATERIALS AND METHODS: Cardiac allograft survival was monitored in different donor/recipient strain combinations. Morphometric analyses on the allograft coronary arteries allowed quantification of vessel intimal thickening. RE...

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Publication status:
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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
Transplantation More from this journal
Volume:
74
Issue:
5
Pages:
740-743
Publication date:
2002-09-01
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
Language:
English
Keywords:
Pubs id:
pubs:135941
UUID:
uuid:1af0df1e-23d1-49ba-9cb4-4eda411fbf41
Local pid:
pubs:135941
Source identifiers:
135941
Deposit date:
2012-12-19

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