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In silico organ modelling in predicting efficacy and safety of new medicines

Abstract:

The development of new medicines faces important challenges due to difficulties in the assessment of their efficacy and their safety in the targeted human population. In silico approaches through the use of mathematical modelling and computer simulations are increasingly being used to overcome some of the limitations of current experimental methods used in the development of new medicines. This chapter describes state-of-the-art in silico approaches for the evaluation of the safety and effica...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/9781782620136-00219

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Role:
Author
Publisher:
Royal Society of Chemistry Publisher's website
Series:
RSC Drug Discovery Series: Human-based Systems for Translational Research
Volume:
2015-January
Issue:
41
Pages:
219-240
Publication date:
2014-12-09
DOI:
EISSN:
2041-3211
ISSN:
2041-3203
ISBN:
9781782623557
Language:
English
Pubs id:
pubs:536581
UUID:
uuid:1ae5e3f5-b298-48f5-a606-e72ab3ef2316
Local pid:
pubs:536581
Source identifiers:
536581
Deposit date:
2015-11-12

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