Journal article
Tracking Antigen-Specific T-Cells during Clinical Tolerance Induction in Humans
- Abstract:
-
Allergen immunotherapy presents an opportunity to define mechanisms of induction of clinical tolerance in humans. Significant progress has been made in our understanding of changes in T cell responses during immunotherapy, but existing work has largely been based on functional T cell assays. HLA-peptide-tetrameric complexes allow the tracking of antigen-specific T-cell populations based on the presence of specific T-cell receptors and when combined with functional assays allow a closer assess...
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Bibliographic Details
- Journal:
- PLoS ONE
- Volume:
- 5
- Issue:
- 6
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
-
1932-6203
Item Description
- Pubs id:
-
pubs:94601
- UUID:
-
uuid:1ac4c76d-9e6a-42e1-b3c9-6738e62e3c32
- Local pid:
- pubs:94601
- Source identifiers:
-
94601
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2010
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