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Journal article

Effect of nutrient deprivation on the viability of intervertebral disc cells.

Abstract:

There is evidence that a fall in nutrient supply leads to disc degeneration but little understanding of the effects of nutrient deprivation on the physiology of disc cells which govern the composition of the disc. We examined the effects of changes in glucose and oxygen concentration and pH on the viability and metabolism of cells from bovine nucleus pulposus. Cells isolated from bovine discs and embedded in alginate beads were cultured under oxygen and glucose concentrations from zero to phy...

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Publication status:
Published

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Publisher copy:
10.1007/s00586-003-0616-x

Authors


Journal:
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Volume:
13
Issue:
8
Pages:
695-701
Publication date:
2004-12-05
DOI:
EISSN:
1432-0932
ISSN:
0940-6719
URN:
uuid:1abb6c8e-bca2-4835-a23d-b2975000c21a
Source identifiers:
238241
Local pid:
pubs:238241

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