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Journal article

Molecular testing for somatic cancer mutations: a survey of current and future testing in UK laboratories.

Abstract:

BACKGROUND: Genetics clinical practice has paid limited attention to non-inherited aspects of cancer, namely mutations occurring during carcinogenesis. These somatic mutations are likely to be the primary determinants of cancer behaviour and treatment response, with a recent example being Her2/Neu gene status and response to Herceptin in breast cancer. AIM: To assess the feasibility of widespread testing of tumours by surveying UK histopathology and genetics laboratories. METHODS: The questi...

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Publication status:
Published

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Publisher copy:
10.1136/jcp.2007.048819

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Population Health
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Wellcome Trust Centre for Human Genetics, Biomedical Research Centre
Role:
Author
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Journal:
Journal of clinical pathology
Volume:
61
Issue:
3
Pages:
373-376
Publication date:
2008-03-05
DOI:
EISSN:
1472-4146
ISSN:
0021-9746
URN:
uuid:1aa337b0-945d-456d-922f-8318dfca9440
Source identifiers:
34147
Local pid:
pubs:34147

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