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Chimpanzee adenoviral vectors as vaccines for outbreak pathogens

Abstract:

The 2014-15 Ebola outbreak in West Africa highlighted the potential for large disease outbreaks caused by emerging pathogens and has generated considerable focus on preparedness for future epidemics. Here we discuss drivers, strategies and practical considerations for developing vaccines against outbreak pathogens. Chimpanzee adenoviral (ChAd) vectors have been developed as vaccine candidates for multiple infectious diseases and prostate cancer. ChAd vectors are safe and induce antigen-specif...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1080/21645515.2017.1383575

Authors


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Department:
Oxford, MSD, NDM, Jenner Institute
More by this author
Department:
Oxford, MSD, NDM, Jenner Institute
More by this author
Department:
Oxford, MSD, NDM, Jenner Institute
More by this author
Department:
Oxford, MSD, NDM, Jenner Institute
More by this author
Department:
Oxford, MSD, NDM, Jenner Institute
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Publisher:
Taylor & Francis Publisher's website
Journal:
Human Vaccines and Immunotherapeutics Journal website
Volume:
13
Issue:
12: The International Society for Vaccines 2016 Annual
Pages:
3020-3032
Publication date:
2017-10-30
Acceptance date:
2017-09-19
DOI:
EISSN:
2164-554X
ISSN:
2164-5515
Pubs id:
pubs:729302
URN:
uri:1a9d62f3-5d24-4feb-bd87-973a2143baa5
UUID:
uuid:1a9d62f3-5d24-4feb-bd87-973a2143baa5
Local pid:
pubs:729302

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