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Viral persistence and disease: cytopathology in the absence of cytolysis.

Abstract:

Realising that viruses could persist and thereby cause chronic disease has been one of the major accomplishments in virology. In this review we will discuss the principles by which viruses can persist and how such persistence can lead to disease. Our focus will be on the ability of certain viruses to interfere subtly with the cell's ability to produce specific differentiated products as hormones, neurotransmitters, cytokines and immunoglobulins, etc., in the absence of their ability to lyse t...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Role:
Author
Journal:
British medical bulletin
Volume:
47
Issue:
4
Pages:
838-851
Publication date:
1991-10-05
EISSN:
1471-8391
ISSN:
0007-1420
URN:
uuid:1a80f2e0-c135-462e-b8c9-82aaff83ab5b
Source identifiers:
34009
Local pid:
pubs:34009

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