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Journal article

Use of prostate-specific antigen (PSA) isoforms for the detection of prostate cancer in men with a PSA level of 2-10 ng/ml: systematic review and meta-analysis.

Abstract:

OBJECTIVE: Measurement of serum prostate-specific antigen (PSA) for the detection of prostate cancer has poor specificity in men with PSA levels between 2 and 10 ng/ml. It has been suggested that measurement of the ratio of free to total PSA (f/tPSA) or complexed PSA (cPSA) might offer an improvement. We performed a systematic review and meta-analysis to evaluate the diagnostic performance of these tests among men with PSA levels between 2 and 10 ng/ml. METHODS: Data on sensitivity and speci...

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Publication status:
Published

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Authors


Roddam, AW More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences, Biomedical Research Centre
Patnick, J More by this author
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Journal:
European urology
Volume:
48
Issue:
3
Pages:
386-399
Publication date:
2005-09-05
DOI:
EISSN:
1873-7560
ISSN:
0302-2838
URN:
uuid:1a733578-22a2-4305-9fb0-0df32a2fa303
Source identifiers:
66456
Local pid:
pubs:66456

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