Journal article
Evaluating beta-amino acids as enantioselective organocatalysts of the Hajos-Parrish-Eder-Sauer-Wiechert reaction.
- Abstract:
- A systematic study of the effect of substitution within the beta-amino acid framework indicates that both beta(2)- and beta(3)-amino acids catalyse the Hajos-Parrish-Eder-Sauer-Wiechert reaction with poor to reasonable levels of enantioselectivity. These results led to the evaluation of the conformationally constrained beta-amino acid (1R,2S)-cispentacin, which catalyses the Hajos-Parrish-Eder-Sauer-Wiechert reaction with comparable or higher levels of enantioselectivity to L-proline.
- Publication status:
- Published
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- Publisher copy:
- 10.1039/b711171a
Authors
- Journal:
- Organic and biomolecular chemistry More from this journal
- Volume:
- 5
- Issue:
- 19
- Pages:
- 3190-3200
- Publication date:
- 2007-10-01
- DOI:
- EISSN:
-
1477-0539
- ISSN:
-
1477-0520
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:33979
- UUID:
-
uuid:1a64226b-bab0-4caa-9e3e-3994ec60ae9d
- Local pid:
-
pubs:33979
- Source identifiers:
-
33979
- Deposit date:
-
2012-12-19
- ARK identifier:
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- Copyright date:
- 2007
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