Subregional mapping of the human lymphocyte-specific protein tyrosine kinase gene (LCK) to 1p35-->p34.3 and its position relative to the 1p marker D1S57.

Journal article

The LCK gene encodes a lymphocyte-specific member of the Src family of protein tyrosine kinases. This gene was previously assigned to human chromosome region 1p35-->p32 by isotopic in situ hybridization. We report here its more refined localization to bands 1p35-->p34.3 by fluorescence in situ hybridization on R-banded metaphase chromosomes and its mapping relative to the reference marker pYNZ2 (D1S57).

Authors: Volpi, E; Romani, M; Siniscalco, M

• Publication status: Published
• Journal: Cytogenetics and cell genetics
• Volume: 67
• Issue: 3
• Pages: 187-189
• Publication date: 1994-01-01
• DOI: 10.1159/000133819
• EISSN: 1424-859X
• ISSN: 0301-0171
• Language: English
• Keywords: Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Chromosome Mapping; Chromosomes, Human, Pair 1; Genetic Markers; Protein-Tyrosine Kinases; In Situ Hybridization, Fluorescence; Molecular Sequence Data; Base Sequence; Lymphocytes; Humans