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Journal article

Ancient Pbx-Hox signatures define hundreds of vertebrate developmental enhancers.

Abstract:

BACKGROUND: Gene regulation through cis-regulatory elements plays a crucial role in development and disease. A major aim of the post-genomic era is to be able to read the function of cis-regulatory elements through scrutiny of their DNA sequence. Whilst comparative genomics approaches have identified thousands of putative regulatory elements, our knowledge of their mechanism of action is poor and very little progress has been made in systematically de-coding them. RESULTS: Here, we identify a...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Files:
Publisher copy:
10.1186/1471-2164-12-637

Authors


Publisher:
BioMed Central Ltd. Publisher's website
Journal:
BMC genomics Journal website
Volume:
12
Issue:
1
Pages:
637
Publication date:
2011-01-01
DOI:
EISSN:
1471-2164
ISSN:
1471-2164
URN:
uuid:1a461467-4d09-4aaf-8533-43a7ab31aee0
Source identifiers:
272940
Local pid:
pubs:272940

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