Journal article

Diastereoselectivity in the alkylations of bicyclic piperidinones

Abstract:: The synthesis of substituted [4.3.0] bicyclic lactams derived from 6- oxo-2-hydroxymethylpiperidine is described. The enolate derived flora these systems can be alkylated with a range of reactive electrophiles; the diastereoselectivity which can be achieved depends on the substitution pattern of the oxazolidine ring system and the nature of the alkylating reagent, and can vary from 1:1 to as much as 10:1.

Publication status:: Published

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APA Style

Mills, C., Heightman, T., Hermitage, S. A., Moloney, M., & Woods, G. (1998). Diastereoselectivity in the alkylations of bicyclic piperidinones. TETRAHEDRON LETTERS, 39(9), 1025–1028.

MLA Style

Mills, C, et al. “Diastereoselectivity in the Alkylations of Bicyclic Piperidinones.” TETRAHEDRON LETTERS, vol. 39, no. 9, 1998, pp. 1025–28.

Chicago Style

Mills, C, T Heightman, SA Hermitage, M Moloney, and G Woods. 1998. “Diastereoselectivity in the Alkylations of Bicyclic Piperidinones.” TETRAHEDRON LETTERS 39 (9): 1025–28.
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Publisher copy:: 10.1016/S0040-4039(97)10694-3

Authors

+ Mills, C More by this author

Role:: Author

+ Heightman, T More by this author

Role:: Author

+ Hermitage, SA More by this author

Role:: Author

+ Moloney, M More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

+ Woods, G More by this author

Role:: Author

Journal:: TETRAHEDRON LETTERS More from this journal
Volume:: 39
Issue:: 9
Pages:: 1025-1028
Publication date:: 1998-02-26
DOI:: 10.1016/S0040-4039(97)10694-3
ISSN:: 0040-4039

Language:: English
Pubs id:: pubs:36441
UUID:: uuid:1a2ba979-3ebd-4f15-9e99-5686ac967c49
Local pid:: pubs:36441
Source identifiers:: 36441
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_1a2ba9793ebd4f159e995686ac967c49

Terms of use

Copyright date:: 1998

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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