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TCF7L2 and diabetes: a tale of two tissues, and of two species.

Abstract:
Human genetics is revealing ever more variants that influence propensity to common diseases, but progress in translating these discoveries into the biological mechanisms responsible for predisposition continues to lag behind. A recent paper in Cell (Boj et al., 2012) using rodent models to examine how diabetes-associated variants near TCF7L2 perturb metabolic regulation provides surprising results.
Publication status:
Published

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Publisher copy:
10.1016/j.cmet.2013.01.011

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author


Journal:
Cell metabolism More from this journal
Volume:
17
Issue:
2
Pages:
157-159
Publication date:
2013-02-01
DOI:
EISSN:
1932-7420
ISSN:
1550-4131


Language:
English
Pubs id:
pubs:384101
UUID:
uuid:1a26ffa5-7b49-4e6e-b7c9-640995ddae16
Local pid:
pubs:384101
Source identifiers:
384101
Deposit date:
2013-11-16
ARK identifier:

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