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Expression profiling reveals metabolic and structural components of extraocular muscles

Abstract:

The extraocular muscles (EOM) are anatomically and physiologically distinct from other skeletal muscles. EOM are preferentially affected in mitochondrial myopathies, but spared in Duchenne's muscular dystrophy. The anatomical and pathophysiological properties of EOM have been attributed to their unique molecular makeup: an allotype. We used expression profiling to define molecular features of the EOM allotype. We found 346 differentially expressed genes in rat EOM compared with tibialis anter...

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Journal:
Physiological Genomics
Volume:
2002
Issue:
9
Pages:
71-84
Publication date:
2002-07-05
ISSN:
1531-2267
URN:
uuid:1a16012f-ddeb-49e7-a917-3efbbbda7bd3
Source identifiers:
373508
Local pid:
pubs:373508

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