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Decreased retinal sensitivity and loss of retinal nerve fibers in multiple system atrophy.

Abstract:

BACKGROUND AND AIM: In a previous study, retinal nerve fiber layer thickness (RNFLT) loss was shown as part of the neurodegenerative process in multiple system atrophy (MSA). Here, we investigate in a larger cohort of MSA patients whether the RNFLT loss translates into respective visual field defects. METHODS: Spectral domain optical coherence tomography was performed in 20 MSA patients (parkinsonian subtype = 12, cerebellar subtype = 8) to quantify peripapillary RNFLT. Visual field (90°) wa...

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Publisher copy:
10.1007/s00417-012-2118-1

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Volume:
251
Issue:
1
Pages:
235-241
Publication date:
2013-01-05
DOI:
EISSN:
1435-702X
ISSN:
0721-832X
URN:
uuid:1a125a46-df46-41b1-bb8c-b9a0f4dfde16
Source identifiers:
371986
Local pid:
pubs:371986

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