Journal article icon

Journal article

KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer.

Abstract:

PURPOSE: Oncogene mutations contribute to colorectal cancer development. We searched for differences in oncogene mutation profiles between colorectal cancer metastases from different sites and evaluated these as markers for site of relapse. EXPERIMENTAL DESIGN: One hundred colorectal cancer metastases were screened for mutations in 19 oncogenes, and further 61 metastases and 87 matched primary cancers were analyzed for genes with identified mutations. Mutation prevalence was compared between...

Expand abstract

Actions


Access Document


Authors


Jorissen, RN More by this author
Expand authors...
Journal:
Clinical cancer research : an official journal of the American Association for Cancer Research
Volume:
17
Issue:
5
Pages:
1122-1130
Publication date:
2011-03-05
DOI:
EISSN:
1557-3265
ISSN:
1078-0432
URN:
uuid:1a0be36c-ae7e-483a-a4ff-351264f549d1
Source identifiers:
112531
Local pid:
pubs:112531

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP