Insulin-like growth factors, their binding proteins, and prostate cancer risk: analysis of individual patient data from 12 prospective studies.

Journal article

BACKGROUND: Some, but not all, published results have shown an association between circulating blood levels of some insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) and the subsequent risk for prostate cancer. PURPOSE: To assess the association between levels of IGFs and IGFBPs and the subsequent risk for prostate cancer. DATA SOURCES: Studies identified in PubMed, Web of Science, and CancerLit. STUDY SELECTION: The principal investigators of all studies that published d...

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Authors: Roddam, A; Allen, N; Appleby, P; Key, T; Ferrucci, L

• Publication status: Published
• Journal: Annals of internal medicine
• Volume: 149
• Issue: 7
• Pages: 461-W88
• Publication date: 2008-10-01
• DOI: 10.7326/0003-4819-149-7-200810070-00006
• EISSN: 1539-3704
• ISSN: 0003-4819
• Language: English
• Keywords: Prostatic Neoplasms; Humans; Somatomedins; Prospective Studies; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor II; Risk Factors; Insulin-Like Growth Factor Binding Protein 2; Middle Aged; Male; Insulin-Like Growth Factor I; Aged; Insulin-Like Growth Factor Binding Proteins