- Abstract:
-
Sensorimotor function and the behavioural responses to a range of doses of subcutaneous apomorphine were assessed in mature (6-8 months) and old (23-26 months) Sprague-Dawley rats of comparable weight. In addition, the locomotor activity response of 12-month-old and 24-month-old rats to continuous infusions (14 days by osmotic minipump) of a selective dopamine D2 agonist. (+)-4-propyl-9-hydroxynaphthoxazine (PHNO, 10 micrograms/h) was investigated. Measures of spontaneous locomotor activity a...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/0006-8993(89)91214-6
-
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- Journal:
- Brain research
- Volume:
- 495
- Issue:
- 1
- Pages:
- 20-30
- Publication date:
- 1989-08-05
- DOI:
- EISSN:
-
1872-6240
- ISSN:
-
0006-8993
- URN:
-
uuid:19fa2fc9-79e3-44c1-b59e-0690e25895e9
- Source identifiers:
-
28380
- Local pid:
- pubs:28380
- Language:
- English
- Keywords:
- Copyright date:
- 1989
Journal article
Effects of ageing on the behavioural responses to dopamine agonists: decreased yawning and locomotion, but increased stereotypy.
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