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Journal article

Exosomal miRNAs as cancer biomarkers and therapeutic targets

Abstract:

Intercommunication between cancer cells and their surrounding and distant environments is key to survival, progression and metastasis of the tumour. Exosomes play a role in this communication process. MicroRNA (miRNA) expression is frequently dysregulated in tumour cells, and is reflected by distinct exosomal miRNA (ex-miRNA) profiles isolated from the bodily fluids of cancer patients. Here, the potential of ex-miRNA as a cancer biomarker and therapeutic target is critically analysed. Exosome...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3402/jev.v5.31292

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Funding agency for:
Wilson, C
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Funding agency for:
Wilson, C
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Funding agency for:
Wilson, C
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Publisher:
Co-Action Publishing Publisher's website
Journal:
Journal of Extracellular Vesicles Journal website
Volume:
5
Pages:
Article: 31292
Publication date:
2016-07-19
DOI:
EISSN:
2001-3078
ISSN:
2001-3078
URN:
uuid:19e0b401-4692-4bab-925e-b81ef9fa231f
Source identifiers:
629978
Local pid:
pubs:629978

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