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Journal article

Evidence of blood-brain barrier dysfunction in human cerebral malaria.

Abstract:

Patients infected with the malaria parasite Plasmodium falciparum may develop a diffuse reversible encephalopathy, termed cerebral malaria. It is unclear how the intraerythrocytic parasite, which sequesters in the cerebral microvasculature but does not enter the brain parenchyma, induces this neurological syndrome. Adhesion of parasitized red blood cells in the brain microvasculature is mediated by specific receptors on the host endothelium, including intercellular adhesion molecule (ICAM)-1,...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Journal:
Neuropathology and applied neurobiology
Volume:
25
Issue:
4
Pages:
331-340
Publication date:
1999-08-01
DOI:
EISSN:
1365-2990
ISSN:
0305-1846
Source identifiers:
31544
Language:
English
Keywords:
Pubs id:
pubs:31544
UUID:
uuid:19d824d1-07b9-45ea-a00c-19215b97d073
Local pid:
pubs:31544
Deposit date:
2012-12-19

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