Development of NIRS method for quality control of drug combination artesunate-azithromycin for the treatment of severe malaria.
Near infrared spectroscopy (NIRS) methods were developed for the determination of analytical content of an antimalarial-antibiotic (artesunate and azithromycin) co-formulation in hard gelatin capsule (HGC). The NIRS consists of pre-processing treatment of spectra (raw spectra and first-derivation of two spectral zones), a unique principal component analysis model to ensure the specificity and then two partial least-squares regression models for the determination content of each active pharmac...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
(Version of record, pdf, 479.8KB)
- Publisher copy:
- Copyright holder:
- Elsevier BV
- Copyright date:
- Copyright © 2012 Elsevier B.V. Open access under CC BY license. Open Access funded by Wellcome Trust.
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record