Journal article icon

Journal article

Mathematical modelling of fibre-enhanced perfusion inside a tissue-engineering bioreactor

Abstract:

We develop a simple mathematical model for forced flow of culture medium through a porous scaffold in a tissue- engineering bioreactor. Porous-walled hollow fibres penetrate the scaffold and act as additional sources of culture medium. The model, based on Darcy’s law, is used to examine the nutrient and shear-stress distributions throughout the scaffold. We consider several configurations of fibres and inlet and outlet pipes. Compared with a numerical solution of the full Navier–Stokes equati...

Expand abstract

Actions


Access Document


Files:

Authors


Robert J Whittaker More by this author
Richard Booth More by this author
Rosemary Dyson More by this author
Clare Bailey More by this author
Louise Parsons Chini More by this author
Expand authors...
Publication date:
2009
URN:
uuid:199fd408-d08f-4440-a43c-14289377b4a4
Local pid:
oai:eprints.maths.ox.ac.uk:913

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP