- Abstract:
-
Transmission ratio distortion (TRD) describes a significant departure from expected Mendelian inheritance ratios that is fundamental to both the biology of reproduction and statistical genetics. The relatively high fetal wastage in humans, with consequent selection of alleles in utero, makes it likely that TRD is prevalent in the human genome. The central region of the human major histocompatibility complex (MHC) is a strong TRD candidate, as it houses a number of immune and regulatory genes ...
Expand abstract - Publication status:
- Published
- Journal:
- Genes and immunity
- Volume:
- 7
- Issue:
- 1
- Pages:
- 51-58
- Publication date:
- 2006-01-05
- DOI:
- EISSN:
-
1476-5470
- ISSN:
-
1466-4879
- URN:
-
uuid:199f8b04-b5f7-4342-896a-f63d323576f1
- Source identifiers:
-
326082
- Local pid:
- pubs:326082
- Copyright date:
- 2006
Journal article
An investigation of transmission ratio distortion in the central region of the human MHC.
Actions
Authors
Bibliographic Details
Item Description
Terms of use
Metrics
Altmetrics
Dimensions
If you are the owner of this record, you can report an update to it here: Report update to this record