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Journal article

Amyotrophic lateral sclerosis.

Abstract:

Amyotrophic lateral sclerosis (ALS) is an idiopathic, fatal neurodegenerative disease of the human motor system. In this Seminar, we summarise current concepts about the origin of the disease, what predisposes patients to develop the disorder, and discuss why all cases of ALS are not the same. In the 150 years since Charcot originally described ALS, painfully slow progress has been made towards answering these questions. We focus on what is known about ALS and where research is heading-from t...

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Publication status:
Published

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Authors


Kiernan, MC More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
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Journal:
Lancet
Volume:
377
Issue:
9769
Pages:
942-955
Publication date:
2011-03-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:19844d0b-d74c-4542-99bf-b667617a5ae2
Source identifiers:
245056
Local pid:
pubs:245056
Language:
English
Keywords:

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