Journal article
Evaluation of Plasmodium vivax Cell-Traversal Protein for Ookinetes and Sporozoites as a Preerythrocytic P. vivax Vaccine
- Abstract:
-
Four different vaccine platforms each targeting the human malaria parasite Plasmodium vivax cell- traversal protein for ookinetes and sporozoites (PvCelTOS) were generated and assessed for protective efficacy. These platforms consisted of a recombinant chimpanzee adenoviral vector ChAd63-PvCelTOS (Ad); a recombinant MVA-PvCelTOS (MVA); a bacteriophage Qβ-PvCelTOS virus-like particle (VLP); and recombinant PvCelTOS protein expressed in eukaryotic HEK293T cells (protein). Inbred BALB/c and outb...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Science Without Borders (Brazil)
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Bibliographic Details
- Publisher:
- American Society for Microbiology Publisher's website
- Journal:
- Clinical and Vaccine Immunology Journal website
- Volume:
- 24
- Issue:
- 4
- Pages:
- e00501-16
- Publication date:
- 2017-02-08
- Acceptance date:
- 2017-01-31
- DOI:
- EISSN:
-
1556-679X
- ISSN:
-
1556-6811
Item Description
- Pubs id:
-
pubs:675024
- UUID:
-
uuid:194ff738-9e0e-4b3b-91c9-1b7d6dd55403
- Local pid:
- pubs:675024
- Deposit date:
- 2017-01-31
Terms of use
- Copyright holder:
- Alves et al
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 Alves et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
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