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Journal article

Metergoline and cyproheptadine suppress prolactin release by a non-5-hydroxytryptaminergic, non-dopaminergic mechanism.

Abstract:
A dispersed rat anterior pituitary cell system has been used to investigate the effects of cyproheptadine and metergoline on prolactin secretion. Both drugs were potent inhibitors of prolactin secretion. However, the inhibition was not antagonized by either 5-hydroxytryptamine or a variety of dopamine antagonists. We conclude that both drugs act through mechanisms that are neither 5-hydroxytryptaminergic nor dopaminergic.
Publication status:
Published

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Publisher copy:
10.1111/j.1476-5381.1980.tb10896.x

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author


Journal:
British journal of pharmacology More from this journal
Volume:
70
Issue:
1
Pages:
5-7
Publication date:
1980-09-01
DOI:
EISSN:
1476-5381
ISSN:
0007-1188


Language:
English
Keywords:
Pubs id:
pubs:138520
UUID:
uuid:19498e39-30d2-4276-88e7-e3ef39870b75
Local pid:
pubs:138520
Source identifiers:
138520
Deposit date:
2012-12-19
ARK identifier:

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