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Oxygen-charged HTK-F6H8 emulsion reduces ischemia-reperfusion injury in kidneys from brain-dead pigs.

Abstract:

BACKGROUND: Prolonged cold ischemia is frequently associated with a greater risk of delayed graft function and enhanced graft failure. We hypothesized that media, combining a high oxygen-dissolving capacity with specific qualities of organ preservation solutions, would be more efficient in reducing immediate ischemia-reperfusion injury from organs stored long term compared with standard preservation media. METHODS: Kidneys retrieved from brain-dead pigs were flushed using either cold histidi...

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Publisher copy:
10.1016/j.jss.2012.06.031

Authors


Nordström, J More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
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Journal:
The Journal of surgical research
Volume:
178
Issue:
2
Pages:
959-967
Publication date:
2012-12-05
DOI:
EISSN:
1095-8673
ISSN:
0022-4804
URN:
uuid:193c9302-b360-4f69-a341-0d5b1ccae19f
Source identifiers:
342486
Local pid:
pubs:342486

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