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Journal article

Identification of a novel type IV pilus gene cluster required for gastrointestinal colonization of Citrobacter rodentium.

Abstract:

Citrobacter rodentium is used as an in vivo model system for clinically significant enteric pathogens such as enterohaemorrhagic Escherichia coli (EHEC) and enteropathogenic E. coli (EPEC). These pathogens all colonize the lumen side of the host gastrointestinal tract via attaching and effacing (A/E) lesion formation. In order to identify genes required for the colonization of A/E-forming pathogens, a library of signature-tagged transposon mutants of C. rodentium was constructed and screened ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
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Journal:
Molecular microbiology
Volume:
48
Issue:
3
Pages:
795-809
Publication date:
2003-05-05
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
URN:
uuid:193709a0-8164-404f-9561-6329f396a59c
Source identifiers:
98252
Local pid:
pubs:98252

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