The primary event in the pathogenesis of severe malaria in Plasmodium falciparum infection is thought to be adherence of trophozoite- and schizont-infected erythrocytes to capillary endothelium, a process called sequestration. Identifying the endothelial molecules used as receptors is an essential step in understanding this disease process. Recent work implicates the membrane glycoprotein CD36 (platelet glycoprotein IV; refs 2-5) and the multi-functional glycoprotein thrombospondin as recepto...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Intercellular adhesion molecule-1 is an endothelial cell adhesion receptor for Plasmodium falciparum.
If you are the owner of this record, you can report an update to it here: Report update to this record