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Journal article

Immunologic characterization of monoclonal antibodies that modulate human IgE binding to the major birch pollen allergen Bet v 1.

Abstract:

BACKGROUND: Bet v 1 and homologous proteins represent major allergens for almost 95% of patients allergic to tree pollen and approximately 70% of those allergic to fruits and vegetables. As yet, no continuous (sequential) IgE epitopes have been determined for Bet v 1, and evidence has accumulated that Bet v 1 IgE epitopes belong to the conformational (discontinuous) type. OBJECTIVE: A panel of 85 mouse monoclonal anti-Bet v 1 antibodies was raised as a tool with which to study the interactio...

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Publication status:
Published

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Authors


Lebecque, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Denépoux, S More by this author
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Journal:
The Journal of allergy and clinical immunology
Volume:
99
Issue:
3
Pages:
374-384
Publication date:
1997-03-05
DOI:
EISSN:
1097-6825
ISSN:
0091-6749
URN:
uuid:18ce9ce6-dbc6-415a-a17c-87b83a807947
Source identifiers:
69747
Local pid:
pubs:69747

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