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Journal article

An infectious transfer and expression system for genomic DNA loci in human and mouse cells.

Abstract:

The recent completion of the human genome sequence allows genomics research to focus on understanding gene complexity, expression, and regulation. However, the routine-use genomic DNA expression systems required to investigate these phenomena are not well developed. Bacterial artificial chromosomes (BACs) and P1-based artificial chromosomes (PACs) have proved excellent tools for the human genome sequencing projects. We describe a system to rapidly and efficiently deliver and express BAC and P...

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Publication status:
Published

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Publisher copy:
10.1038/nbt1101-1067

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Nature biotechnology
Volume:
19
Issue:
11
Pages:
1067-1070
Publication date:
2001-11-05
DOI:
EISSN:
1546-1696
ISSN:
1087-0156
URN:
uuid:187a0508-b856-47d5-bef9-4084f4f3ad1a
Source identifiers:
113931
Local pid:
pubs:113931

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