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UKPDS 20: plasma leptin, obesity, and plasma insulin in type 2 diabetic subjects.

Abstract:

We measured plasma leptin and insulin concentrations across a spectrum of obesity in 829 white Caucasian, 154 Afro-Caribbean, and 204 Asian type 2 diabetic subjects. Although the leptin concentrations covered a large range, there were no subgroups of diabetic subjects with very high or low leptin levels that would suggest mutations in the leptin gene or leptin receptor gene comparable to the obese diabetic ob/ob and db/db mice models respectively. In all three ethnic groups, leptin concentrat...

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Publication status:
Published

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Publisher copy:
10.1210/jc.82.2.654

Authors


Widjaja, A More by this author
Stratton, IM More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
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Journal:
The Journal of clinical endocrinology and metabolism
Volume:
82
Issue:
2
Pages:
654-657
Publication date:
1997-02-05
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
URN:
uuid:18789ab8-1efd-4939-9ade-bcd337a6cee6
Source identifiers:
12819
Local pid:
pubs:12819

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