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Preparation of multicompartment sub-micron particles using a triple-needle electrohydrodynamic device.

Abstract:

Control over the size and morphology of polymeric carriers for drug delivery systems is essential to optimize their functionality. In the current study, we demonstrate the feasibility of using an electrohydrodynamic process with a triple-needle device to prepare nearly mono-dispersed, spherical, tri-layered sub-micron particles. Three biocompatible polymer solutions of poly (lactic-co-glycolic acid) (PLGA), polycaprolactone (PCL) and polymethylsilsesquioxane (PMSQ) were used to prepare partic...

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Publication status:
Published

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Publisher copy:
10.1016/j.jcis.2013.07.033

Authors


Edirisinghe, M More by this author
Journal:
Journal of colloid and interface science
Volume:
409
Pages:
245-254
Publication date:
2013-11-05
DOI:
EISSN:
1095-7103
ISSN:
0021-9797
URN:
uuid:18768f49-5694-40ed-a884-d52c19ba5caf
Source identifiers:
420435
Local pid:
pubs:420435

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