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MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial.

Abstract:

BACKGROUND: Individuals with diabetes are at increased risk of cardiovascular morbidity and mortality, although typically their plasma concentrations of LDL cholesterol are similar to those in the general population. Previous evidence about the effects of lowering cholesterol in people with diabetes has been limited, and most diabetic patients do not currently receive cholesterol-lowering therapy despite their increased risk. METHODS: 5963 UK adults (aged 40-80 years) known to have diabetes, ...

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Publication status:
Published

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Authors


Collins, R More by this author
Armitage, J More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit, BHF Centre of Research Excellence
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Journal:
Lancet
Volume:
361
Issue:
9374
Pages:
2005-2016
Publication date:
2003-06-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:18693a49-499b-4561-93b3-b4d7616393bd
Source identifiers:
38647
Local pid:
pubs:38647

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