Airway inflammation, airway responsiveness and cough before and after inhaled budesonide in patients with eosinophilic bronchitis.

Journal article

Eosinophilic bronchitis is a common cause of chronic cough, characterized by sputum eosinophilia similar to that seen in asthma, but unlike asthma the patients have no objective evidence of variable airflow obstruction or airway hyperresponsiveness. The reason for the different functional associations is unclear. The authors have tested the hypothesis that in eosinophilic bronchitis the inflammation is mainly localized in the upper airway. In an open study the authors measured the lower (prov...

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Authors: Brightling, C; Ward, R; Wardlaw, A; Pavord, I

• Journal: European respiratory journal
• Volume: 15
• Issue: 4
• Pages: 682-686
• Publication date: 2000-04-01
• DOI: 10.1034/j.1399-3003.2000.15d10.x
• EISSN: 1399-3003
• ISSN: 0903-1936
• Language: English
• Keywords: Reference Values; Middle Aged; Glucocorticoids; Aged; Humans; Adult; Administration, Topical; Nasal Lavage Fluid; Male; Dose-Response Relationship, Drug; Budesonide; Bronchial Hyperreactivity; Anti-Inflammatory Agents; Eosinophilia; Administration, Inhalation; Cough; Confidence Intervals; Bronchitis; Female; Treatment Outcome