Journal article

A novel series of oligomers from 4-aminomethyl-tetrahydrofuran-2-carboxylates with 2,4-cis and 2,4-trans stereochemistry

Abstract:: Two tetrahydrofuran-based γ-amino acids [2,4-cis and 2,4-trans] were subjected to iterative peptide-coupling procedures to afford dimeric, tetrameric and hexameric carbopeptoids in good yield. These homooligomers were prepared for secondary structural study-to ascertain the conformational preference inherent in the monomer units. The l-xylo oligomers were protected with triethylsilyl ethers to increase the range of solvents suitable for structural investigation. Initial secondary structure data indicate the presence of hydrogen-bonded conformations in the l-ribo series. © 2006 Elsevier Ltd. All rights reserved.

Publication status:: Published

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APA Style

Edwards, A., Sanjayan, G., Hachisu, S., Tranter, G., & Fleet, G. (2006). A novel series of oligomers from 4-aminomethyl-tetrahydrofuran-2-carboxylates with 2,4-cis and 2,4-trans stereochemistry. TETRAHEDRON, 62(33), 7718–7725.

MLA Style

Edwards, A, et al. “A Novel Series of Oligomers from 4-Aminomethyl-Tetrahydrofuran-2-Carboxylates with 2,4-Cis and 2,4-Trans Stereochemistry.” TETRAHEDRON, vol. 62, no. 33, 2006, pp. 7718–25.

Chicago Style

Edwards, A, G Sanjayan, S Hachisu, G Tranter, and G Fleet. 2006. “A Novel Series of Oligomers from 4-Aminomethyl-Tetrahydrofuran-2-Carboxylates with 2,4-Cis and 2,4-Trans Stereochemistry.” TETRAHEDRON 62 (33): 7718–25.
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Publisher copy:: 10.1016/j.tet.2006.05.067

Authors

+ Edwards, A More by this author

Role:: Author

+ Sanjayan, G More by this author

Role:: Author

+ Hachisu, S More by this author

Role:: Author

+ Tranter, G More by this author

Role:: Author

+ Fleet, G More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

Journal:: TETRAHEDRON More from this journal
Volume:: 62
Issue:: 33
Pages:: 7718-7725
Publication date:: 2006-08-14
DOI:: 10.1016/j.tet.2006.05.067
ISSN:: 0040-4020

Language:: English
Keywords:: peptidomimetics

gamma amino acids

foldamers

sugar amino acids
Pubs id:: pubs:40017
UUID:: uuid:182f864c-9424-49cb-bcfa-11b800d16213
Local pid:: pubs:40017
Source identifiers:: 40017
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_182f864c942449cbbcfa11b800d16213

Terms of use

Copyright date:: 2006

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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