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Computational modelling of cell spreading and tissue regeneration in porous scaffolds.

Abstract:

Improved biological and mechanical functionality of musculoskeletal tissue-engineered constructs is required for clinical application, which can only be achieved by comprehensive multidisciplinary research. This review focuses on the contribution of computational modelling as a framework for obtaining an integrated understanding of key processes, which include: nutrient transport and utilization, matrix formation, cell population dynamics, cell attachment and migration, and local cell-cell in...

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Publication status:
Published

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Authors


Sengers, BG More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Oreffo, RO More by this author
Journal:
Biomaterials
Volume:
28
Issue:
10
Pages:
1926-1940
Publication date:
2007-04-05
DOI:
EISSN:
1878-5905
ISSN:
0142-9612
URN:
uuid:18282ff9-9aa5-412e-8c04-01a242bbd949
Source identifiers:
357203
Local pid:
pubs:357203

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