The structure of the DNA oligomer d(G-G-G-G-C-C-C-C) has been determined at a resolution of 2.5 A by single-crystal X-ray methods. There are two strands in the asymmetric unit, and these coil about each other to form a right-handed double-helix of the A-type with Watson-Crick hydrogen bonds between base-pairs. The helix has a shallow minor groove and a deep, water-filled major groove; almost all exposed functional groups on the DNA are hydrated, and 106 ordered solvent molecules have been fou...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
The crystal structure of d(G-G-G-G-C-C-C-C). A model for poly(dG).poly(dC).
If you are the owner of this record, you can report an update to it here: Report update to this record