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SAGE analysis of cell types involved in tolerance induction.

Abstract:

Investigations into the mechanisms of immunological tolerance are currently hindered by a paucity of convenient markers, both for the identification and isolation of tolerant cell types and for monitoring the establishment of tolerance in in vivo models. Although high-affinity autoreactive T cells are deleted in the thymus during the establishment of central tolerance, escaping autoreactive cells require modulation in the periphery. Dendritic cells (DC) and regulatory T cells (Treg) are both ...

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Methods in molecular biology (Clifton, N.J.)
Volume:
380
Pages:
225-251
Publication date:
2007
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
URN:
uuid:181bf69b-6ff0-4b26-90f6-df4a77f02f7a
Source identifiers:
25744
Local pid:
pubs:25744

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