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Toward a neuropsychological theory of antidepressant drug action: increase in positive emotional bias after potentiation of norepinephrine activity.

Abstract:

OBJECTIVE: Antidepressants that increase serotonin or norepinephrine in the brain are effective in treating depression, but there is no neuropsychological account of how these changes relieve depressive states. Cognitive theories suggest that biases in information processing lead depressed patients to make unrealistically negative judgments about themselves and the world. METHOD: A single dose of the noradrenergic antidepressant reboxetine or placebo was administered to 24 healthy volunteers...

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Publication status:
Published

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Publisher copy:
10.1176/appi.ajp.160.5.990

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
Journal:
The American journal of psychiatry
Volume:
160
Issue:
5
Pages:
990-992
Publication date:
2003-05-05
DOI:
EISSN:
1535-7228
ISSN:
0002-953X
URN:
uuid:1819db7b-af03-4d12-8923-42d7a0bbbc32
Source identifiers:
97943
Local pid:
pubs:97943

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